Product Review
Copper Amino Isolate Serum 3 1:1 (CAIS3) | Manufacturing and Formulation Insights
This page provides an ingredient-level review of Copper Amino Isolate Serum 3 1:1 (CAIS3) by NIOD. Below you’ll find the publicly available ingredient list, a dynamic ingredient breakdown linked to the FormuNova ingredient database, and a formula structure overview intended for cosmetic founders, product developers, and brand teams researching competitor product architecture in modern face serums and related Beauty & Personal Care categories. This page is a formulation and manufacturing review and does not imply or state any association between FormuNova and NIOD.
Aqua (Water), Glycerin, Tripeptide-29, Copper Tripeptide-1, Tripeptide-1, Myristoyl Nonapeptide-3, Trifluoroacetyl Tripeptide-2, Acetyl Tetrapeptide-2, Sodium Hyaluronate Crosspolymer, Glycogen, Propanediol, Pentylene Glycol, Dextran, Dimethyl Isosorbide, Ethoxydiglycol, Isoceteth-20, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
Formulation Deep Dive
Copper Amino Isolate Serum 3 1:1 (CAIS3) by NIOD is engineered as a water-based, peptide-forward serum built around a high concentration of copper peptide and a broad supporting peptide architecture. The carrier is a streamlined aqueous system of Aqua and Glycerin, with Glycerin doubling as the primary humectant. The formula's defining feature is its position high in the ingredient list for Copper Tripeptide-1, paired with a layered peptide complex of Tripeptide-29, Tripeptide-1, Myristoyl Nonapeptide-3, Trifluoroacetyl Tripeptide-2, and Acetyl Tetrapeptide-2 to diversify the signaling profile. Hydration and substantivity are reinforced by Sodium Hyaluronate Crosspolymer for a cushioned, film-forming moisture layer, while Glycogen and Dextran act as biopolymer conditioning agents that support skin feel and texture. A solvent and penetration-modifier system of Propanediol, Pentylene Glycol, Dimethyl Isosorbide, and Ethoxydiglycol keeps the actives soluble and aids even spreadability, with Isoceteth-20 serving as a solubilizer for any sparingly water-soluble components. The result is a lightweight, fast-absorbing fluid with no oils or silicones. Preservation follows a hybrid clean-label strategy combining Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, and Chlorphenesin.
Formula Structure Overview
This formula has a 81% match with ingredients from our research database. Among the matched ingredients, the main functional themes identified are categorized as barrier support, anti-aging agent, hydrator, and strengthener ingredients.
Barrier Support
Anti-Aging Agent
Strengthener
Ingredient Analysis
About our ratingsThe manufacturing partners for NIOD are not publicly disclosed. Many brands work with multiple contract manufacturers across different regions depending on production volume, product type, and regulatory requirements.
Exact sales numbers for NIOD are not publicly disclosed.
NIOD has successfully captured market share by focusing on a successful balance of marketing and formulation.
Replicating that success requires more than just copying a formula, it requires identifying a marketing strategy that is unique to your brand’s audience, associated with a great product offering.
At FormuNova, we specialize in helping brands move past imitation to create high-performance product offerings with potential to outperform the current market leaders. Let’s discuss your launch strategy.
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This page provides an independent ingredient analysis of publicly available cosmetic products for research purposes. All trademarks, brand names, and product names are the property of their respective owners. FormuNova does not claim to be affiliated with, endorsed by, or sponsored by the brands mentioned on this page. Product images, when shown, are used solely for identification and commentary under fair use principles.

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