The Beauty & Personal Care Brand Builder Series

Ingredient Deep Dive

Nicotiana Benthamiana Hexapeptide-40 SH-Polypeptide-86

The Beauty & Personal Care Brand Builder Series

Ingredient Deep Dive

Nicotiana Benthamiana Hexapeptide-40 SH-Polypeptide-86

The Bioengineered Keratin-Type Peptide

Nicotiana Benthamiana Hexapeptide-40 SH-Polypeptide-86 is a bioengineered, keratin-type peptide used in premium hair systems to support fuller, healthier-looking hair. It is bioengineered — expressed in Nicotiana benthamiana (a tobacco relative) as a sustainable, vegan production platform, then purified for cosmetic use.

It is used to support the look of stronger, healthier, fuller-looking hair, and pairs well with other peptides and scalp actives.

Quick Insights

Ingredient Rating:

GOOD

Type of Ingredient:

Strengthener and Conditioner

Intended Function:

A bioengineered plant-expressed peptide used to support the look of stronger, fuller hair.

Common Applications:

Used in hair & scalp serums and shampoos and conditioners.

Target Audience:

Brands formulating modern, vegan peptide-based hair and scalp serums.

Also Known As:

Nicotiana Benthamiana Hexapeptide-40 SH-Polypeptide-86, Bioengineered Hexapeptide-40 SH-Polypeptide-86

Benefits of Nicotiana Benthamiana Hexapeptide-40 SH-Polypeptide-86

A bioengineered, plant-expressed peptide that supports the appearance of stronger, fuller-looking hair.

Fuller-Looking Hair: Supports the appearance of denser, healthier-looking hair.
Strengthening (Look): Helps hair look and feel more resilient.
Conditioning: Supports smooth, well-conditioned hair fibers.
Bioengineered & Vegan: Produced by precision plant expression, not animal- or petro-derived.
Modern Peptide: Layers into advanced peptide hair systems.

How It Works

This keratin-type peptide echoes sequences found in hair’s structural proteins and is used to support the appearance of denser, well-conditioned hair. As a cosmetic active its benefits are described in terms of the appearance and feel of the hair and scalp, not as a medical or hair-growth treatment.

Formulating with Nicotiana Benthamiana Hexapeptide-40 SH-Polypeptide-86

Nicotiana Benthamiana Hexapeptide-40 SH-Polypeptide-86 is water-soluble and added to the water phase at low levels, typically at cool-down. It pairs well with other peptides and humectants. Observe good manufacturing and preservation practice.

Safety Analysis

Nicotiana Benthamiana Hexapeptide-40 SH-Polypeptide-86 is well tolerated at cosmetic use levels. Claims are limited to the appearance and feel of hair. As always, substantiate the finished product’s safety (e.g. patch / HRIPT testing) in line with MoCRA requirements.

References

https://incidecoder.com/ingredients/nicotiana-benthamiana-hexapeptide-40-sh-poly…

https://cosmeticanalysis.com/cosmetic-ingredients/nicotiana-benthamiana-hexapept…

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