This ingredient blend harnesses multiple forms of hyaluronan — including Crosspolymer, Conventional Sodium Hyaluronate, Acetylated, and Hydrolyzed variants — so formulating teams can deliver layered and sustained hydration. The Sodium Hyaluronate Crosspolymer forms a stable three-dimensional film on the skin’s surface, providing prolonged moisture retention, reinforcing barrier integrity, and smoothing fine lines. Meanwhile, low molecular weight Sodium Hyaluronate and Hydrolyzed Sodium Hyaluronate penetrate deeper into the epidermis, drawing in water for plumping and firmness. Sodium Acetylated Hyaluronate displays enhanced skin affinity and superior water-binding capacity — reportedly absorbing three times more moisture than standard forms — and exhibits anti-aging benefits including inhibition of collagen-degrading MMP‑1 enzymes and reduction of nasolabial and crow’s‑feet wrinkles. Pentylene Glycol supports the formula as a humectant, carrier, and mild antimicrobial enhancer, aiding ingredient distribution and texture (general industry role, widely recognized).
Though primarily leveraged in skincare, this blend may benefit scalp and hair hydrating formulations. The crosspolymer and high-burden hyaluronates can form occlusive moisture films on the scalp or hair shaft, improving softness, reducing frizz, and bolstering barrier function against dryness. Lower‑molecular hyaluronate forms may permeate the follicular cuticle, aiding in hydration from within. Pentylene Glycol’s humectant and skin-conditioning properties also translate well in haircare, enhancing moisture retention and product texture; however, direct scientific studies of this exact mineral combination in hair care remain limited.

Quick Insights
Ingredient Rating:
GREAT
Type of Ingredient:
Hydrator, Moisturizer, Texture Enhancer, Soother, Barrier Support and Anti-Aging Agent
Intended Function:
Deliver multi-depth and long-lasting hydration, enhance skin barrier resilience, and smooth texture while supporting anti-aging performance.
Common Applications:
Formulated into serums, night masks, moisturizers, lotions, and facial primers to achieve both immediate and extended hydrating efficacy; also adaptable for scalp/hair treatments targeting dryness and barrier fortification.
Target Audience:
Brands targeting dry, mature, dehydrated, or compromised skin requiring long-term hydration and anti-aging support; and those developing high-performance scalp/haircare where moisture retention and smoothing are critical.
Also Known As:
Crosslinked Hyaluronic Acid / Hyaluronan Crosspolymer, Sodium Hyaluronate (the salt form of Hyaluronic Acid), Sodium Acetylated Hyaluronate (acetyl-modified HA with improved hydration), Hydrolyzed Sodium Hyaluronate (fragmented HA for deeper penetration).
Safety Analysis
Hyaluronate derivatives are generally well-tolerated; they mimic naturally occurring skin polysaccharides, minimizing irritation risk. The crosspolymer and acetylated forms are chemically stable and non-sensitizing under typical usage levels. The crosslinked crosspolymer is resistant to enzymatic degradation, ensuring extended benefits and consistent performance — a marked advantage over conventional HA that is more susceptible to degradation. Multi-molecular-weight blends mitigate issues like rapid loss of hydration or lack of penetration. Used as a mild humectant and preservative booster, Pentylene Glycol is generally regarded as safe in cosmetic use, with minimal risk of irritation when used in moderate concentration. It supports delivery without significantly altering formula pH.

References
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