Cetrimonium Chloride is a quaternary ammonium surfactant widely valued in haircare formulations for its cationic conditioning benefits. Its positively charged molecules bind electrostatically to the negatively charged keratin in the hair, effectively reducing static buildup and smoothing cuticles. This mechanism enhances detangling, improves manageability, and imparts a smooth, lustrous finish. In curl-enhancing products, it helps define structure, retain moisture, shield against heat, and resist frizz—contributing to improved curl formation, bounce, and overall polish.
In skincare, Cetrimonium Chloride acts as an antimicrobial surfactant, facilitating emulsification and aiding gentle cleansing by helping oils and impurities detach from the skin for effective rinsing. It also exhibits mild preservative properties, helping suppress microbial growth to prolong product stability, especially in aqueous formulas.

Quick Insights
Ingredient Rating:
GOOD
Type of Ingredient:
Texture Enhancer, Conditioner, Anti-Frizz Agent and Volume Control Agent
Intended Function:
To condition and detangle hair, control static and frizz, facilitate cleansing, and help preserve formula integrity.
Common Applications:
Found in conditioners, hair masks, leave-in treatments, shampoos, styling creams, curl-defining products, and sanitizing cleansers.
Target Audience:
Ideal for brands developing high-performance haircare targeting curly, frizzy, dry, or heat-stressed hair, as well as cleansing and moisturizing formulations requiring gentle conditioning and preservation.
Also Known As:
Cetyltrimethylammonium Chloride (CTAC).
Safety Analysis
Regulatory guidance from the Cosmetic Ingredient Review affirms Cetrimonium Chloride is safe in rinse-off formulations up to approximately 10% and in leave-on products up to 0.25–1%, depending on formulation type. At higher concentrations, it may cause mild irritation; patch testing and adherence to recommended levels are advised.

References
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