Serenoa repens (saw palmetto) extract is a lipido-sterolic concentrate rich in free fatty acids (primarily lauric, oleic, myristic, and palmitic acids) and minor phytosterols. In vitro and ex vivo data indicate this lipid fraction can inhibit both type-1 and type-2 5-α-reductase, the enzymes that convert testosterone to dihydrotestosterone (DHT). By helping moderate the DHT axis in sebocytes, saw palmetto is frequently positioned as an “oil-control support” active for shiny or congestion-prone skin. Beyond sebum balance, the extract demonstrates antioxidant and anti-inflammatory behaviors reported in dermatology literature (e.g., modulation of COX-2/5-LOX pathways), which formulators leverage in lightweight emulsions and gel-creams designed to visibly calm redness while maintaining a non-greasy sensorial profile.
Because the scalp’s 5-α-reductase activity and inflammatory milieu strongly influence oiliness and scalp comfort, S. repens is increasingly included in rinse-off and leave-on scalp serums, micellar shampoos, and balancing conditioners. The ingredient’s primary cosmetic value here is supporting healthy sebum levels and scalp comfort. In practical formulation terms, its fatty acid profile also imparts mild emolliency, improving slip and after-feel in hydroalcoholic toners, oil-in-water emulsions, and anhydrous scalp oils.

Quick Insights
Ingredient Rating:
GOOD
Type of Ingredient:
Emollient, Conditioner, Antioxidant, Soother, Anti-Inflammatory Agent, Barrier Support and Oil Control Agent
Intended Function:
Support balanced sebum appearance and soothe visible irritation on skin and scalp via lipido-sterolic bioactivity and antioxidant action.
Common Applications:
Mattifying moisturizers, anti-shine serums/toners, scalp-balancing leave-ons, clarifying shampoos, lightweight conditioners, after-shave balms.
Target Audience:
Oily or combination skin; congestion-prone complexions; shiny or easily irritated T-zones; oily or uncomfortable scalp.
Also Known As:
Serenoa Serrulata Fruit Extract, Serenoa Repens Extract, Saw Palmetto Extract, Sabal Palm Extract, 84604-15-9.
Safety Analysis
Regulatory status. European databases list Serenoa serrulata fruit extract as a skin-conditioning cosmetic ingredient with no specific concentration ban under standard use; formulators must still substantiate safety for their finished product and follow local labeling rules.
Topical tolerability. Dermatology literature and cosmetic use reports generally indicate good cutaneous tolerance in rinse-off and leave-on formats. Combination topical studies aimed at oily skin (saw palmetto with sesame/argan actives) have documented reductions in measured sebum alongside acceptable tolerability.
Population cautions. Although systemic exposure from topical cosmetics is expected to be low, many brands conservatively advise avoiding use during pregnancy and lactation for DHT-pathway actives as a precautionary stance. Conduct HRIPT/patch testing on the finished product, monitor fragrance/allergen load, and document MoCRA-aligned safety substantiation.

References
Ready to launch your next product?
We offer US-based Beauty & Personal care private label, product development and manufacturing, starting with low minimum order quantity.We specialize in helping brands innovate and launch new products that resonate with their audiences.
Explore product launch options for your brand today.



Not Quite Ready To Start?
Signup to our newsletter to receive the latest in cosmetic industry trends, expert advice, formulation tips, and insider-only offers.
Thinking about launching something else? We can create a wide range of custom formulas for your brand. Explore our product development capabilities and ingredients.











