Sodium DNA, known as sodium deoxyribonucleate or polydeoxyribonucleotide (PDRN), is a polynucleotide compound derived primarily from salmon milt. Also entitled as Salmon DNA, this ingredient functions as a potent regenerative agent in skincare, promoting fibroblast proliferation and enhancing extracellular matrix synthesis. This activity leads to improved skin elasticity, thickness, and hydration, making it effective in reducing fine lines, wrinkles, and signs of photoaging. Additionally, PDRN exhibits antioxidant properties, scavenging free radicals and protecting skin cells from oxidative stress. Its ability to stimulate cellular repair mechanisms also contributes to its efficacy in wound healing and skin rejuvenation applications.

In hair care, Sodium DNA has been incorporated into formulations aimed at combating hair loss and promoting scalp health. It supports the proliferation of dermal papilla cells and enhances the vitality of hair follicles, potentially leading to increased hair density and strength. By improving microcirculation and delivering essential nucleotides to the scalp, it aids in restoring the natural hair growth cycle and mitigating conditions like androgenic alopecia. Furthermore, its moisturizing and anti-inflammatory properties help maintain scalp homeostasis, reducing dryness and irritation.