Serenoa Repens (Saw Palmetto) Fruit Oil is a lipid-rich botanical derivative increasingly utilized in topical formulations targeting scalp and hair health. Its most prominent mechanism — 5α‑reductase inhibition — helps reduce the conversion of testosterone to dihydrotestosterone (DHT), the androgen responsible for follicular miniaturization. Studies report promising outcomes: topical and oral applications yielded up to a 60 % improvement in hair quality, 27 % increase in hair count, and enhanced density in over 80 % of patients with androgenetic alopecia or telogen effluvium. The oil is also valued for its anti‑inflammatory and antioxidant phytosterols and fatty acids, which may soothe irritated scalps and support follicular integrity.
In skincare, Serenoa Repens Fruit Oil lends a calming, antioxidative dimension to formulations. Rich in plant sterols — such as beta-sitosterol — and fatty acids that help mitigate redness, its topical application can reinforce skin barrier function while tempering inflammation. This dual functionality for both scalp and skin positions it as an adaptable asset in advanced cosmetic formulations.

Quick Insights
Ingredient Rating:
GOOD
Type of Ingredient:
Conditioner, Antioxidant, Strengthener, Anti-Inflammatory Agent, Barrier Support, Oil Control Agent and Blood Flow Modulator
Intended Function:
To inhibit 5α‑reductase on the scalp — thereby mitigating DHT-induced follicular shrinkage — while imparting antioxidant protection and soothing effects to skin and scalp.
Common Applications:
Used in formulations like anti‑hair‑loss shampoos, conditioners, scalp serums, masks, and soothing facial oils or creams targeting redness, barrier repair, and oxidative damage.
Target Audience:
Ideal for formulations aimed at brand owners targeting consumers experiencing early-stage thinning hair, sensitive or inflamed scalps, androgenetic alopecia, or individuals seeking botanical-based skincare that calms and strengthens.
Also Known As:
Serenoa Repens Fruit Extract, Saw Palmetto Extract/Oil.
Safety Analysis
Serenoa Repens Fruit Oil is generally well tolerated in topical use. Evidence suggests low incidence of adverse skin reactions. However, systemic use (e.g., oral supplements) may pose mild side effects and interact with hormone-related conditions or blood-thinning medications. Topical application reduces systemic exposure significantly, but patch testing is prudent, especially in formulations containing other actives.

References
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